{"id":10338,"date":"2023-10-06T23:21:11","date_gmt":"2023-10-06T20:21:11","guid":{"rendered":"https:\/\/bt.qu.edu.iq\/\/?p=10338"},"modified":"2024-03-09T17:42:03","modified_gmt":"2024-03-09T14:42:03","slug":"%d8%b1%d8%b3%d8%a7%d9%84%d8%a9-%d9%85%d8%a7%d8%ac%d8%b3%d8%aa%d9%8a%d8%b1-%d9%81%d9%8a-%d9%83%d9%84%d9%8a%d8%a9-%d8%a7%d9%84%d8%aa%d9%82%d8%a7%d9%86%d8%a7%d8%aa-%d8%a7%d9%84%d8%a7%d8%ad%d9%8a%d8%a7-2","status":"publish","type":"post","link":"https:\/\/bt.qu.edu.iq\/?p=10338","title":{"rendered":"\u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0641\u064a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0642\u0627\u0646\u0627\u062a \u0627\u0644\u0627\u062d\u064a\u0627\u0626\u064a\u0629 \u062a\u0646\u0627\u0642\u0634 \u0627\u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0645\u0646\u0627\u0639\u064a \u0648\u0627\u0644\u0648\u0631\u0627\u062b\u064a \u0644\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0645\u0635\u0627\u0628\u0627\u062a \u0628\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636"},"content":{"rendered":"\n

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\u062a\u0647\u062f\u0641 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0647\u0630\u0647 \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0625\u0644\u0649 \u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0627\u0633\u0633 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0648\u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636 \u0645\u0646 \u062e\u0644\u0627\u0644 \u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u0639\u0644\u0627\u0645\u0627\u062a \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0648\u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0627\u0644\u0643\u0634\u0641 \u0639\u0646 \u062a\u0639\u062f\u062f \u0627\u0644\u0645\u062a\u063a\u0627\u064a\u0631\u0627\u062a \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u0629 \u0641\u064a \u062c\u064a\u0646 \u0643\u062a\u0644\u0629 \u0627\u0644\u062f\u0647\u0648\u0646 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u0627\u0644\u0633\u0645\u0646\u0629 (FTO).\u0648\u062a\u062d\u062f\u064a\u062f \u0645\u0633\u062a\u0648\u0649 (TNF-\u03b1) \u0648(IL-1\u03b2) \u0627\u0644\u0633\u064a\u062a\u0648\u0643\u064a\u0646\u0627\u062a \u0627\u0644\u0645\u0639\u0632\u0632\u0629 \u0644\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u0641\u064a \u0627\u0644\u0645\u0635\u0644 \u0627\u0644\u0645\u0631\u062a\u0628\u0637\u0629 \u0628\u062d\u062f\u0648\u062b \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636.
\u0623\u0638\u0647\u0631\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0623\u0646 \u0645\u0631\u0636\u0649 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636 \u0644\u062f\u064a\u0647\u0645 \u0648\u0632\u0646 \u062c\u0633\u0645 \u0623\u0639\u0644\u0649 \u0648\u0645\u0624\u0634\u0631 \u0643\u062a\u0644\u0629 \u0627\u0644\u062c\u0633\u0645 \u0623\u0639\u0644\u0649. \u0648\u0627\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0647\u0631\u0645\u0648\u0646\u0627\u062a \u0627\u0644\u062e\u0635\u0648\u0628\u0629 (LH) \u0648 (FSH) \u0627\u0638\u0647\u0631\u062a \u0627\u062e\u062a\u0644\u0627\u0641\u0627 \u0645\u0639\u0646\u0648\u064a\u0627 \u0643\u0628\u064a\u0631\u0627 \u062c\u062f\u0627 \u0641\u064a \u0645\u0631\u0636\u0649 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636.
\u0623\u062b\u0628\u062a\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u0645\u0646\u0627\u0639\u064a\u0629 \u0623\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a IL-1\u03b2 \u0648 TNF\u2013\u03b1 \u0623\u0638\u0647\u0631\u062a \u0632\u064a\u0627\u062f\u0629 \u0645\u0639\u0646\u0648\u064a\u0629 \u0643\u0628\u064a\u0631\u0629 \u062c\u062f\u0627 \u0641\u064a \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0645\u0635\u0627\u0628\u0627\u062a \u0628\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636 P < 0.001) ) \u0648\u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u0645\u0633\u062a\u0648\u0649 IL-1\u03b2 \u0641\u064a \u0627\u0644\u0645\u0631\u0636\u0649 (3779.09 \u00b1 739.90) pg\/ml. \u0648 \u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u0645\u0633\u062a\u0648\u0649 TNF\u2013\u03b1 \u0641\u064a \u0627\u0644\u0645\u0631\u0636\u0649 (527.45 \u00b1 128.92) ng\/ml . \u0643\u0634\u0641\u062a \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0639\u0646 \u0627\u0631\u062a\u0628\u0627\u0637\u0627\u062a \u0625\u064a\u062c\u0627\u0628\u064a\u0629 \u0628\u064a\u0646 \u0645\u0633\u062a\u0648\u064a\u0627\u062a IL-1\u03b2\u0648 TNF\u2013\u03b1 \u0641\u064a \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0645\u0635\u0627\u0628\u0627\u062a \u0628\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636 \u060c \u0645\u0645\u0627 \u064a\u062f\u0644 \u0639\u0644\u0649 \u0645\u0634\u0627\u0631\u0643\u0629 \u0627\u0644\u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u0627\u0644\u062a\u0647\u0627\u0628\u064a\u0629 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629.
\u0648\u0641\u0642\u0627 \u0644\u0646\u062a\u0627\u0626\u062c \u0645\u0646\u062d\u0646\u0649 \u0631\u0648\u0643 ROC curve \u0623\u0646 \u0645\u0633\u062a\u0648\u0649 IL-1\u03b2 \u064a\u0645\u0643\u0646 \u0627\u0633\u062a\u062e\u062f\u0627\u0645\u0647 \u0643\u0639\u0644\u0627\u0645\u0629 \u062a\u0634\u062e\u064a\u0635\u064a\u0629 \u0642\u064a\u0645\u0629 \u0641\u064a \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0627\u0644\u0645\u0628\u0643\u0631 \u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636 . \u0643\u0627\u0646\u062a \u0627\u0644\u0645\u0633\u0627\u062d\u0629 \u062a\u062d\u062a \u0627\u0644\u0645\u0646\u062d\u0646\u0649 IL-1\u03b2 0.925 (0.874- 0.976).
\u0623\u062b\u0628\u062a\u062a \u0646\u062a\u0627\u0626\u062c \u0627\u0644\u062f\u0631\u0627\u0633\u0629 \u0627\u0644\u062c\u0632\u064a\u0626\u064a\u0629 \u0644\u0644\u062a\u063a\u0627\u064a\u0631 \u0627\u0644\u0648\u0631\u0627\u062b\u064a \u0644\u062c\u064a\u0646 FTO (rs9939609) -T\/A \u0623\u0646 \u0627\u0644\u0645\u0631\u0636\u0649 \u0628\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062c\u064a\u0646\u064a TA \u0645\u0627 \u064a\u0642\u0631\u0628 \u0645\u0646 \u0645\u0631\u062a\u064a\u0646 \u0627\u0643\u062b\u0631 \u0639\u0631\u0636\u0629 \u0644\u062a\u0637\u0648\u064a\u0631 \u0627\u0644\u0645\u0631\u0636 \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u0645\u0631\u0636\u0649 \u0628\u0627\u0644\u0623\u0646\u0645\u0627\u0637 \u0627\u0644\u062c\u064a\u0646\u064a\u0629 \u0627\u0644\u0627\u062e\u0631\u0649 \u0648 \u0643\u0627\u0646 A-allele \u064a\u0631\u062a\u0628\u0637 \u0628\u0634\u0643\u0644 \u0627\u064a\u062c\u0627\u0628\u064a \u0645\u0639 \u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636 \u06281.42 \u0636\u0639\u0641\u0627. \u0643\u0644\u0627 \u0627\u0644\u0646\u0645\u0637\u064a\u0646 \u0627\u0644\u0648\u0631\u0627\u062b\u064a\u064a\u0646 (AA) \u0648 (TA) \u062a\u0639\u062a\u0628\u0631 \u0639\u0648\u0627\u0645\u0644 \u062e\u0637\u0648\u0631\u0629 \u0644\u0645\u062a\u0644\u0627\u0632\u0645\u0629 \u062a\u0643\u064a\u0633 \u0627\u0644\u0645\u0628\u0627\u064a\u0636 (OR=1.46) \u0648 OR=1.94)) \u0639\u0644\u0649 \u0627\u0644\u062a\u0648\u0627\u0644\u064a.
\u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u0645\u0633\u062a\u0648\u0649 IL-1\u03b2 \u0627\u0639\u0644\u0649 \u0641\u064a \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u062d\u0645\u0644\u0648\u0646 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062c\u064a\u0646\u064a ((AA \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0627\u062e\u0631\u0649 \u0644\u0643\u0646 \u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641 \u063a\u064a\u0631 \u0645\u0639\u0646\u0648\u064a (P= 0.132). \u0643\u0627\u0646 \u0645\u062a\u0648\u0633\u0637 \u0645\u0633\u062a\u0648\u0649 TNF-\u03b1 \u0627\u0639\u0644\u0649 \u0641\u064a \u0627\u0644\u0645\u0631\u0636\u0649 \u0627\u0644\u0630\u064a\u0646 \u064a\u062d\u0645\u0644\u0648\u0646 \u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062c\u064a\u0646\u064a (AA) \u0628\u0627\u0644\u0645\u0642\u0627\u0631\u0646\u0629 \u0645\u0639 \u0627\u0644\u0645\u062c\u0645\u0648\u0639\u0627\u062a \u0627\u0644\u0627\u062e\u0631\u0649 \u0644\u0643\u0646 \u0627\u0644\u0627\u062e\u062a\u0644\u0627\u0641 \u063a\u064a\u0631 \u0645\u0639\u0646\u0648\u064a .(P= 0.763)<\/p>\n\n\n\n

\n
\"\"<\/a><\/figure>\n\n\n\n
\"\"<\/a><\/figure>\n<\/figure>\n\n\n\n

<\/h2>\n\n\n\n

<\/h2>\n","protected":false},"excerpt":{"rendered":"

\u0627\u062c\u0631\u062a \u0643\u0644\u064a\u0629 \u0627\u0644\u062a\u0642\u0627\u0646\u0627\u062a \u0627\u0644\u0627\u062d\u064a\u0627\u0626\u064a\u0629 \u0645\u0646\u0627\u0642\u0634\u0629 \u0631\u0633\u0627\u0644\u0629 \u0645\u0627\u062c\u0633\u062a\u064a\u0631 \u0628\u0639\u0646\u0648\u0627\u0646 \u062f\u0631\u0627\u0633\u0629 \u0645\u0646\u0627\u0639\u064a\u0629 \u0648\u062c\u0632\u064a\u0626\u064a\u0629 \u0644\u0628\u0639\u0636 \u0627\u0644\u0646\u0633\u0627\u0621 \u0641\u064a \u0645\u062d\u0627\u0641\u0638\u0629 \u0627\u0644\u062f\u064a\u0648\u0627\u0646\u064a\u0629 \u0644\u0644\u0637\u0627\u0644\u0628\u0629 \u0648\u0633\u0646 \u0623\u0628\u0627\u0630\u0631 \u062d\u0645\u0632\u0629 … \u0627\u0642\u0631\u0623 \u0623\u0643\u062b\u0631<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":10344,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[],"class_list":["post-10338","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-5"],"_links":{"self":[{"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/10338","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10338"}],"version-history":[{"count":1,"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/10338\/revisions"}],"predecessor-version":[{"id":21097,"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/10338\/revisions\/21097"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/10344"}],"wp:attachment":[{"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10338"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10338"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bt.qu.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10338"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}